2021 49ers Schedule

The NFL released the schedules for the 2021 NFL Season. The 49ers open the season in Detroit – Fun Fact: the last two times the 49ers opened the season in Detroit, they went onto win the Super Bowl those seasons.

The 49ers home opener will be in primetime on Sunday Night Football against the Green Bay Packers.

Outside the Packers in primetime the 49ers will have four more prime time games.

WeekDateTimeOpponentTV
1Sun, Sep 1210:00 amat LionsFOX
2Sun, Sep 1910:00 amat EaglesFOX
3Sun, Sep 265:20 pmvs PackersNBC
4Sun, Oct 31:05 pmvs SeahawksFOX
5Sun, Oct 101:25 pmat CardinalsFOX
6BYE
7Sun, Oct 245:20 pmvs ColtsNBC
8Sun, Oct 3110:00 amat BearsFOX
9Sun, Nov 71:25 pmvs CardinalsFOX
10Mon, Nov 155:15 pmvs RamsESPN
11Sun, Nov 2110:00 amat JaguarsFOX
12Sun, Nov 281:25 pmvs VikingsFOX
13Sun, Dec 55:20 pmat SeahawksNBC
14Sun, Dec 1210:00 amat BengalsCBS
15Sun, Dec 191:05 pmvs FalconsCBS
16Thu, Dec 235:20 pmat TitansNFLN
17Sun, Jan 21:05 pmvs TexansCBS
18Sun, Jan 91:25 pmat RamsFOX

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